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The LANCA three-component reaction to highly substituted β-ketoenamides – versatile intermediates for the synthesis of functionalized pyridine, pyrimidine, oxazole and quinoxaline derivatives

The LANCA three-component reaction of lithiated alkoxyallenes LA, nitriles N and carboxylic acids CA leads to β-ketoenamides KE in good to excellent yields. The scope of this reaction is very broad and almost all types of nitriles and carboxylic acids have successfully been used. The alkoxy group in...

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Bibliografiske detaljer
Udgivet i:Beilstein J Org Chem
Main Authors: Lechel, Tilman, Kumar, Roopender, Bera, Mrinal K, Zimmer, Reinhold, Reissig, Hans-Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423578/
https://ncbi.nlm.nih.gov/pubmed/30931007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.61
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