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Synthesis of highly functionalized 2,2'-bipyridines by cyclocondensation of β-ketoenamides – scope and limitations

The scope of a flexible route to unsymmetrically functionalized bipyridines is described. Starting from 1,3-diketones 1a–e, the corresponding β-ketoenamines 2a–e were converted into different β-ketoenamides 3a–g by N-acylation with 2-pyridinecarboxylic acid derivatives. These β-ketoenamides were tre...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Hommes, Paul, Reissig, Hans-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979911/
https://ncbi.nlm.nih.gov/pubmed/27559368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.112
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