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Synthesis and investigations into the anticancer and antibacterial activity studies of β-carboline chalcones and their bromide salts
A series of sixteen β-carbolines, bearing chalcone moiety at C-1 position, were prepared from easily accessible 1-acetyl-β-carboline and various aldehydes under basic conditions followed by N(2)-alkylation using different alkyl bromides. The prepared compounds were evaluated for in vitro cytotoxicit...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423518/ https://ncbi.nlm.nih.gov/pubmed/29573910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.03.033 |
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