Sequential one-pot synthesis of bis(indolyl)glyoxylamides: Evaluation of antibacterial and anticancer activities

A series of bis(indolyl)glyoxylamides 10a–n has been designed and synthesized. In situ generated indole-3-glyoxalylchloride from the reaction of readily available indole 9 with oxalyl chloride was treated with tryptamine to produce bis(indolyl)glyoxylamides 10a–n in 82–93% yields. All the synthesize...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Bioorg Med Chem Lett
Autores principales: Tantak, Mukund P., Gupta, Vishakha, Nikhil, Kumar, Arun, V., Singh, Rajnish Prakash, Jha, Prabhat Nath, Shah, Kavita, Kumar, Dalip
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899133/
https://ncbi.nlm.nih.gov/pubmed/27173802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.04.080
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares