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One-pot synthesis and in-vitro anticancer evaluation of 5-(2′-indolyl)thiazoles
A series of 5-(2′-indolyl)thiazoles were synthesized and evaluated for their cytotoxicity against selected human cancer cell lines. The reaction of thioamides 3 with 3-tosyloxypentane-2,4-dione 4 led to in situ formation of 5-acetylthiazole 5 which upon treatment with arylhydrazines 6 in polyphospho...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810428/ https://ncbi.nlm.nih.gov/pubmed/27021742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23401 |
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