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Covalent Modification by Glyoxals Converts Cytochrome c Into its Apoptotically Competent State
The effects of glycation by glyoxal (Gly) and methylglyoxal (MGly) on the early and late conformational alterations in Cytochrome c (Cyt c) were studied. Spectroscopic measurements revealed that Cyt c undergo certain conformational alterations and exposure of heme upon overnight incubation with Gly...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423144/ https://ncbi.nlm.nih.gov/pubmed/30886207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41282-2 |
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