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Rapid genetic and phenotypic changes in Pseudomonas aeruginosa clinical strains during ventilator-associated pneumonia

Treatment with antibiotics leads to the selection of isolates with increased resistance. We investigated if evolution towards resistance was associated with virulence changes, in the context of P. aeruginosa ventilator-associated pneumonia (VAP). Four patients were selected because they had multiple...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Persyn, Elise, Sassi, Mohamed, Aubry, Marc, Broly, Martin, Delanou, Sandie, Asehnoune, Karim, Caroff, Nathalie, Crémet, Lise
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423012/
https://ncbi.nlm.nih.gov/pubmed/30886315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41201-5
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