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Rapid genetic and phenotypic changes in Pseudomonas aeruginosa clinical strains during ventilator-associated pneumonia

Treatment with antibiotics leads to the selection of isolates with increased resistance. We investigated if evolution towards resistance was associated with virulence changes, in the context of P. aeruginosa ventilator-associated pneumonia (VAP). Four patients were selected because they had multiple...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Persyn, Elise, Sassi, Mohamed, Aubry, Marc, Broly, Martin, Delanou, Sandie, Asehnoune, Karim, Caroff, Nathalie, Crémet, Lise
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423012/
https://ncbi.nlm.nih.gov/pubmed/30886315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41201-5
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