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Advanced methods for accessing protein shape-shifting present new therapeutic opportunities
A protein is a dynamic shape-shifter whose function is determined by the set of structures it adopts. Unfortunately, atomically-detailed structures are only available for a few conformations of any given protein, and these structures have limited explanatory and predictive power. Here, we provide a...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422738/ https://ncbi.nlm.nih.gov/pubmed/30555007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.11.007 |
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