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Haplotype Analysis of β-Thalassaemia Major and Carriers with Filipino β°-Deletion in Sabah, Malaysia

OBJECTIVE: The Filipino β°-deletion has been reported as a unique mutation in East Malaysia with a severe phenotype due to the complete absence of β-globin chain synthesis. In this study, the haplotype patterns of the β-globin gene cluster were used to relate the human genetic variation to this spec...

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Bibliografiske detaljer
Udgivet i:Malays J Med Sci
Main Authors: Teh, Lai Kuan, Elizabeth, George, Lai, Mei I, Wong, Lily, Ismail, Patimah
Format: Artigo
Sprog:Inglês
Udgivet: Penerbit Universiti Sains Malaysia 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422544/
https://ncbi.nlm.nih.gov/pubmed/30914848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21315/mjms2018.25.4.6
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