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A novel gap-PCR with high resolution melting analysis for the detection of α-thalassaemia Southeast Asian and Filipino β(0)-thalassaemia deletion

Homozygosity for the α-thalassaemia Southeast Asian (α-SEA) and Filipino β(0)-thalassaemia (β-FIL) deletions can cause serious complications leading to foetal death or life-long blood transfusions. A rapid and accurate molecular detection assay is essential in populations where the deletions are com...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Leng Kho, Siew, Heng Chua, Kek, George, Elizabeth, Tan, Jin Ai Mary Anne
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568469/
https://ncbi.nlm.nih.gov/pubmed/26365497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13937
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