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High Throughput Molecular Confirmation of β-Thalassemia Mutations Using Novel TaqMan Probes

β-Thalassemia is a public health problem where 4.5% of Malaysians are β-thalassemia carriers. The genetic disorder is caused by defects in the β-globin gene complex which lead to reduced or complete absence of β-globin chain synthesis. Five TaqMan genotyping assays were designed and developed to det...

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Detalhes bibliográficos
Main Authors: Kho, Siew Leng, Chua, Kek Heng, George, Elizabeth, Tan, Jin Ai Mary Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649372/
https://ncbi.nlm.nih.gov/pubmed/23429513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s130202506
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