2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines

2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ), a novel synthesized combretastatin A-4
(CA-4) analogue, is identified as a microtubule inhibitor and has been shown to exert anticancer activity in breast cancer cells. Here, we found that SQ reversed epidermal growth factor (EGF)-induced m...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Zheng, Dayong, Chang, Xing, Liu, Yang, Xu, Jingwen, Gou, Wenfeng, Li, Zengqiang, Zuo, Daiying, Zhang, Weige, Wu, Yingliang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422509/
https://ncbi.nlm.nih.gov/pubmed/30514153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1537578
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