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The effect of antigen dose on T cell-targeting vaccine outcome

During the past 3–4 decades, an increasing amount of evidence has pointed to the complex role of the antigen dose or T cell receptor (TCR) stimulation strength on the subsequent type, duration and “flavor” or quality of the response. Antigen dose was initially shown to impact Th1/Th2 bias, and later...

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Detalles Bibliográficos
Publicado en:Hum Vaccin Immunother
Autores principales: Billeskov, Rolf, Beikzadeh, Babak, Berzofsky, Jay A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422501/
https://ncbi.nlm.nih.gov/pubmed/30277831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2018.1527496
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