The TRPP2-dependent channel of renal primary cilia also requires TRPM3

Primary cilia of renal epithelial cells express several members of the transient receptor potential (TRP) class of cation-conducting channel, including TRPC1, TRPM3, TRPM4, TRPP2, and TRPV4. Some cases of autosomal dominant polycystic kidney disease (ADPKD) are caused by defects in TRPP2 (also calle...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kleene, Steven J., Siroky, Brian J., Landero-Figueroa, Julio A., Dixon, Bradley P., Pachciarz, Nolan W., Lu, Lu, Kleene, Nancy K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422334/
https://ncbi.nlm.nih.gov/pubmed/30883612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214053
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