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Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors

Centrins (CETN1–4) are ubiquitous and conserved EF-hand–family Ca(2+)-binding proteins associated with the centrosome, basal body, and transition zone. Deletion of CETN1 or CETN2 in mice causes male infertility or dysosmia, respectively, without affecting photoreceptor function. However, it remains...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Ying, Guoxin, Frederick, Jeanne M., Baehr, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422093/
https://ncbi.nlm.nih.gov/pubmed/30647131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006371
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