Multimodal profiling of single-cell morphology, electrophysiology and gene expression using Patch-seq

Neurons exhibit a rich diversity of morphological phenotypes, electrophysiological properties and gene expression patterns. Understanding how these different characteristics are interrelated at the single-cell level has been difficult due to the lack of techniques for multimodal profiling of individ...

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Veröffentlicht in:Nat Protoc
Hauptverfasser: Cadwell, Cathryn R., Scala, Federico, Li, Shuang, Livrizzi, Giulia, Shen, Shan, Sandberg, Rickard, Jiang, Xiaolong, Tolias, Andreas S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422019/
https://ncbi.nlm.nih.gov/pubmed/29189773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.120
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