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Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy

Head and neck cancer is the sixth leading cancer by incidence worldwide. Unfortunately, drug resistance and relapse are the principal limitations of clinical oncology for many patients, and the failure of conventional treatments is an extremely demoralizing experience. It is therefore crucial to fin...

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Publicat a:Oxid Med Cell Longev
Autors principals: Fernandez-Gil, Beatriz I., Guerra-Librero, Ana, Shen, Ying-Qiang, Florido, Javier, Martínez-Ruiz, Laura, García-López, Sergio, Adan, Christian, Rodríguez-Santana, César, Acuña-Castroviejo, Darío, Quiñones-Hinojosa, Alfredo, Fernández-Martínez, José, Abdel Moneim, Ahmed E., López, Luis C., Rodríguez Ferrer, José M., Escames, Germaine
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421819/
https://ncbi.nlm.nih.gov/pubmed/30944696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7187128
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