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Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy

Head and neck cancer is the sixth leading cancer by incidence worldwide. Unfortunately, drug resistance and relapse are the principal limitations of clinical oncology for many patients, and the failure of conventional treatments is an extremely demoralizing experience. It is therefore crucial to fin...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Fernandez-Gil, Beatriz I., Guerra-Librero, Ana, Shen, Ying-Qiang, Florido, Javier, Martínez-Ruiz, Laura, García-López, Sergio, Adan, Christian, Rodríguez-Santana, César, Acuña-Castroviejo, Darío, Quiñones-Hinojosa, Alfredo, Fernández-Martínez, José, Abdel Moneim, Ahmed E., López, Luis C., Rodríguez Ferrer, José M., Escames, Germaine
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421819/
https://ncbi.nlm.nih.gov/pubmed/30944696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7187128
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