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Melatonin Enhances Cisplatin and Radiation Cytotoxicity in Head and Neck Squamous Cell Carcinoma by Stimulating Mitochondrial ROS Generation, Apoptosis, and Autophagy

Head and neck cancer is the sixth leading cancer by incidence worldwide. Unfortunately, drug resistance and relapse are the principal limitations of clinical oncology for many patients, and the failure of conventional treatments is an extremely demoralizing experience. It is therefore crucial to fin...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Fernandez-Gil, Beatriz I., Guerra-Librero, Ana, Shen, Ying-Qiang, Florido, Javier, Martínez-Ruiz, Laura, García-López, Sergio, Adan, Christian, Rodríguez-Santana, César, Acuña-Castroviejo, Darío, Quiñones-Hinojosa, Alfredo, Fernández-Martínez, José, Abdel Moneim, Ahmed E., López, Luis C., Rodríguez Ferrer, José M., Escames, Germaine
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421819/
https://ncbi.nlm.nih.gov/pubmed/30944696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7187128
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