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Assembly of transgenic human P301S Tau is necessary for neurodegeneration in murine spinal cord
A pathological pathway leading from soluble monomeric to insoluble filamentous Tau is characteristic of many human neurodegenerative diseases, which also exhibit dysfunction and death of brain cells. However, it is unknown how the assembly of Tau into filaments relates to cell loss. To study this, w...
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| Publicado no: | Acta Neuropathol Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6421678/ https://ncbi.nlm.nih.gov/pubmed/30885267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0695-5 |
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