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Dynamics of DNA replication in a eukaryotic cell

Each genomic locus in a eukaryotic cell has a distinct average time of replication during S phase that depends on the spatial and temporal pattern of replication initiation events. Replication timing can affect genomic integrity because late replication is associated with an increased mutation rate....

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Сохранить в:
Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Kelly, Thomas, Callegari, A. John
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421431/
https://ncbi.nlm.nih.gov/pubmed/30718387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818680116
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