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Evaluating the involvement of cerebral microvascular endothelial Na(+)/K(+)-ATPase and Na(+)-K(+)-2Cl(–) co-transporter in electrolyte fluxes in an in vitro blood–brain barrier model of dehydration

The blood–brain barrier (BBB) is involved in brain water and salt homeostasis. Blood osmolarity increases during dehydration and water is osmotically extracted from the brain. The loss of water is less than expected from pure osmotic forces, due to brain electrolyte accumulation. Although the underl...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Lykke, Kasper, Assentoft, Mette, Hørlyck, Sofie, Helms, Hans CC, Stoica, Anca, Toft-Bertelsen, Trine L, Tritsaris, Katerina, Vilhardt, Frederik, Brodin, Birger, MacAulay, Nanna
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421245/
https://ncbi.nlm.nih.gov/pubmed/28994331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17736715
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