Analysis of resistance-associated substitutions in acute hepatitis C virus infection by deep sequencing across six genotypes and three continents.

Several direct-acting antivirals (DAA) have now been approved for the treatment of chronic HCV infections, opening the door to imminent interferon-free regiments containing molecules targeting the viral protease (NS3), phosphoprotein (NS5A) and the polymerase (NS5B). Resistance-associated variants (...

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Publicat a:J Viral Hepat
Autors principals: Eltahla, Auda A., Rodrigo, Chaturaka, Betz-Stablein, Brigid, Grebely, Jason, Applegate, Tanya, Luciani, Fabio, Schinkel, Janke, Dore, Gregory J., Page, Kimberly, Bruneau, Julie, Morris, Meghan D., Cox, Andrea L., Kim, Arthur Y., Shoukry, Naglaa H., Lauer, Georg M., Maher, Lisa, Hellard, Margaret, Prins, Maria, Lloyd, Andrew R., Bull, Rowena A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421067/
https://ncbi.nlm.nih.gov/pubmed/27666440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvh.12615
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