Activation of Estrogen Receptor Alpha by Decitabine Inhibits Osteosarcoma Growth and Metastasis

Osteosarcoma is a malignant tumor in the bone that originates from normal osteoblasts or osteoblast precursors. Normal osteoblasts express estrogen receptor alpha (ERα); however, osteosarcomas do not due to promoter DNA methylation. Here we show that treatment of 143B osteosarcoma cells with Decitab...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Osuna, Maria Angeles Lillo, Garcia-Lopez, Jesus, Ayachi, Ikbale El, Fatima, Iram, Khalid, Aysha B., Kumpati, Jerusha, Slayden, Alexandria V., Seagroves, Tiffany N., Miranda-Carboni, Gustavo A., Krum, Susan A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420872/
https://ncbi.nlm.nih.gov/pubmed/30593524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1255
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