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BET inhibitors potentiate chemotherapy and killing of SPOP-mutant colon cancer cells via induction of DR5
Bromodomain and extra-terminal domain (BET) family proteins such as BRD4 are epigenetic readers that control expression of a number of oncogenic proteins. Targeting this family of proteins has recently emerged as a promising anticancer approach. BET inhibitors (BETi), either alone or in combination...
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| 發表在: | Cancer Res |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420862/ https://ncbi.nlm.nih.gov/pubmed/30674532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3223 |
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