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Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder

The major depressive disorder (MDD) working group of the Psychiatric Genomics Consortium (PGC) has published a genome-wide association study (GWAS) for MDD in 130,664 cases, identifying 44 risk variants. We used these results to investigate potential drug targets and repurposing opportunities. We bu...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Gaspar, Héléna A., Gerring, Zachary, Hübel, Christopher, Middeldorp, Christel M., Derks, Eske M., Breen, Gerome
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420656/
https://ncbi.nlm.nih.gov/pubmed/30877270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0451-4
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