The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification

Voltage-gated Ca(2+) (Ca(V)) channels trigger glucose-induced insulin secretion in pancreatic beta-cell and their dysfunction increases diabetes risk. These heteromeric complexes include the main subunit alpha1, and the accessory ones, including subunit gamma that remains unexplored. Here, we demons...

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Gepubliceerd in:Commun Biol
Hoofdauteurs: Luan, Cheng, Ye, Yingying, Singh, Tania, Barghouth, Mohammad, Eliasson, Lena, Artner, Isabella, Zhang, Enming, Renström, Erik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420573/
https://ncbi.nlm.nih.gov/pubmed/30911681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0351-4
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