PKM2 promotes reductive glutamine metabolism

OBJECTIVE: Pyruvate kinases M (PKM), including the PKM1 and PKM2 isoforms, are critical factors in glucose metabolism. PKM2 promotes aerobic glycolysis, a phenomenon known as " the Warburg effect”. The purpose of this study was to identify the roles of PKM2 in regulating cellular metabolism. ME...

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Detalhes bibliográficos
Publicado no:Cancer Biol Med
Main Authors: Liu, Miao, Wang, Yuanyuan, Ruan, Yuxia, Bai, Changsen, Qiu, Li, Cui, Yanfen, Ying, Guoguang, Li, Binghui
Formato: Artigo
Idioma:Inglês
Publicado em: Chinese Anti-Cancer Association 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420233/
https://ncbi.nlm.nih.gov/pubmed/30891326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2018.0122
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