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Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia
Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine nitrogen is disposed to avoid over-accumulating ammonia remains to be determined. Here we identify a metabolic flux of glutamine to secretor...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6331631/ https://ncbi.nlm.nih.gov/pubmed/30643150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08033-9 |
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