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A non-canonical JAGGED1 signal to JAK2 mediates osteoblast commitment in cranial neural crest cells
During craniofacial development, cranial neural crest (CNC) cells migrate into the developing face and form bone through intramembranous ossification. Loss of JAGGED1 (JAG1) signaling in the CNC cells is associated with maxillary hypoplasia or maxillary bone deficiency (MBD) in mice and recapitulate...
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| Publicado no: | Cell Signal |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420215/ https://ncbi.nlm.nih.gov/pubmed/30529759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.12.002 |
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