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Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients
JAGGED1 mutations cause Alagille syndrome, comprising a constellation of clinical findings, including biliary, cardiac and craniofacial anomalies. Jagged1, a ligand in the Notch signaling pathway, has been extensively studied during biliary and cardiac development. However, the role of JAGGED1 durin...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465692/ https://ncbi.nlm.nih.gov/pubmed/22156581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr575 |
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