Modulation of the heart's electrical properties by the anticonvulsant drug retigabine

Retigabine, currently used as antiepileptic drug, has a wide range of potential medical uses. Administration of the drug in patients can lead to QT interval prolongation in the electrocardiogram and to cardiac arrhythmias in rare cases. This suggests that the drug may perturb the electrical properti...

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Bibliographic Details
Published in:Toxicol Appl Pharmacol
Main Authors: Rubi, Lena, Kovar, Michael, Zebedin-Brandl, Eva, Koenig, Xaver, Dominguez-Rodriguez, Manuel, Todt, Hannes, Kubista, Helmut, Boehm, Stefan, Hilber, Karlheinz
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420109/
https://ncbi.nlm.nih.gov/pubmed/28641963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.06.018
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