The anticonvulsant retigabine is a subtype selective modulator of GABA (A) receptors

OBJECTIVE: Within its range of therapeutic plasma concentrations, the anticonvulsant retigabine (ezogabine) is believed to selectively act on Kv7 channels. Here, the contribution of specific γ‐aminobutyric acid (GABA)(A) receptor subtypes to the antiseizure effects of retigabine was investigated. ME...

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Bibliografiske detaljer
Udgivet i:Epilepsia
Main Authors: Treven, Marco, Koenig, Xaver, Assadpour, Elham, Gantumur, Enkhbileg, Meyer, Christiane, Hilber, Karlheinz, Boehm, Stefan, Kubista, Helmut
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Full‐length Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949651/
https://ncbi.nlm.nih.gov/pubmed/25779225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12950
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