Cargando...

Modulation of allosteric coupling by mutations: from protein dynamics and packing to altered native ensembles and function

A large body of work has gone into understanding the effect of mutations on protein structure and function. Conventional treatments have involved quantifying the change in stability, activity and relaxation rates of the mutants with respect to the wild-type protein. However, it is now becoming incre...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Curr Opin Struct Biol
Autor Principal: Naganathan, Athi N
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420056/
https://ncbi.nlm.nih.gov/pubmed/30268910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2018.09.004
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!