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A Bayesian model-free approach to combination therapy phase I trials using censored time-to-toxicity data
The product of independent beta probabilities escalation (PIPE) design for dual-agent phase I dose-escalation trials is a Bayesian model-free approach for identifying multiple maximum tolerated dose combinations of novel combination therapies. Despite only being published in 2015, the PIPE design ha...
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| 出版年: | J R Stat Soc Ser C Appl Stat |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420054/ https://ncbi.nlm.nih.gov/pubmed/30880843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/rssc.12323 |
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