TLR9-mediated dendritic cell activation uncovers mammalian ganglioside species with specific ceramide backbones that activate invariant natural killer T cells

CD1d-restricted invariant natural killer T (iNKT) cells represent a heterogeneous population of lipid-reactive T cells that are involved in many immune responses, mediated through T-cell receptor (TCR)–dependent and/or independent activation. Although numerous microbial lipid antigens (Ags) have bee...

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Опубликовано в: :PLoS Biol
Главные авторы: Paget, Christophe, Deng, Shenglou, Soulard, Daphnée, Priestman, David A., Speca, Silvia, von Gerichten, Johanna, Speak, Anneliese O., Saroha, Ashish, Pewzner-Jung, Yael, Futerman, Anthony H., Mallevaey, Thierry, Faveeuw, Christelle, Gu, Xiaobo, Platt, Frances M., Sandhoff, Roger, Trottein, François
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420026/
https://ncbi.nlm.nih.gov/pubmed/30822302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000169
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