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Increased methylation upstream of the MEG3 promotor is observed in acute myeloid leukemia patients with better overall survival
BACKGROUND: The delta-like non-canonical Notch ligand 1 (DLK1)-maternally expressed 3(MEG3) locus (DLK1-MEG3 locus) plays a critical role in the maintenance and differentiation of hematopoietic stem cells. Accumulating evidence implicates the imprinted genes from this locus, DLK1 and MEG3, in the de...
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| Vydáno v: | Clin Epigenetics |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6419839/ https://ncbi.nlm.nih.gov/pubmed/30876483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0643-z |
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