Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells

BACKGROUND: One of the challenging problems of current radio-chemotherapy is recurrence and metastasis of cancer cells that survive initial treatment. We propose that one of the unwanted effects of radiochemotherapy is the release from damaged (“leaky”) cells of nucleotides such as ATP and UTP that...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Schneider, Gabriela, Glaser, Talita, Lameu, Claudiana, Abdelbaset-Ismail, Ahmed, Sellers, Zachariah Payne, Moniuszko, Marcin, Ulrich, Henning, Ratajczak, Mariusz Z.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657356/
https://ncbi.nlm.nih.gov/pubmed/26597723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0469-z
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