Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells

Pharmacological mobilization of hematopoietic stem progenitor cells (HSPCs) from bone marrow (BM) into peripheral blood (PB) is a result of mobilizing agent-induced “sterile inflammation” in the BM microenvironment due to complement cascade (ComC) activation. Here we provide evidence that ATP, as an...

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Publicado en:Leukemia
Autores principales: Adamiak, Mateusz, Bujko, Kamila, Cymer, Monika, Plonka, Monika, Glaser, Talita, Kucia, Magda, Ratajczak, Janina, Ulrich, Henning, Abdel-Latif, Ahmed, Ratajczak, Mariusz Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127086/
https://ncbi.nlm.nih.gov/pubmed/29725032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0122-0
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