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Mobilization of hematopoietic stem cells as a result of innate immunity-mediated sterile inflammation in the bone marrow microenvironment—the involvement of extracellular nucleotides and purinergic signaling

Hematopoietic stem/progenitor cells (HSPCs) circulate in peripheral blood (PB) under normal conditions and their number increases in response to stress, inflammation, tissue/organ injury, and may increase up to 100-fold after administration of mobilization-inducing drugs. Mounting evidence suggests...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Ratajczak, Mariusz Z, Adamiak, Mateusz, Plonka, Monika, Abdel-Latif, Ahmed, Ratajczak, Janina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940655/
https://ncbi.nlm.nih.gov/pubmed/29556022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-018-0087-z
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