Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...

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Detalles Bibliográficos
Publicado en:Drug Deliv
Main Authors: Hendel, Kristoffer K., Bagger, Charlotte, Olesen, Uffe H., Janfelt, Christian, Hansen, Steen H., Haedersdal, Merete, Lerche, Catharina M.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419659/
https://ncbi.nlm.nih.gov/pubmed/30859849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1574937
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