Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways

BACKGROUND: Non-canonical Wnt pathways play important roles in liver fibrosis. Notum is a newly discovered inhibitor to Wnt proteins. This study was to investigate anti-fibrotic effects of Notum. METHODS: 53 patients with hepatitis B virus (HBV) infection as well as a cell co-culture system of LX-2...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biol Res
Auteurs principaux: Li, Wenting, Yu, Xiaolan, Zhu, Chuanlong, Wang, Zheng, Zhao, Zonghao, Li, Yi, Zhang, Yonghong
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419342/
https://ncbi.nlm.nih.gov/pubmed/30871618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-019-0217-8
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