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Evaluation of linear models and missing value imputation for the analysis of peptide-centric proteomics

BACKGROUND: Several methods to handle data generated from bottom-up proteomics via liquid chromatography-mass spectrometry, particularly for peptide-centric quantification dealing with post-translational modification (PTM) analysis like reversible cysteine oxidation are evaluated. The paper proposes...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Berg, Philip, McConnell, Evan W., Hicks, Leslie M., Popescu, Sorina C., Popescu, George V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419331/
https://ncbi.nlm.nih.gov/pubmed/30871482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2619-6
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