Removal of Protein-Bound Uremic Toxins during Hemodialysis Using a Binding Competitor

BACKGROUND AND OBJECTIVES: Current hemodialysis techniques fail to efficiently remove the protein-bound uremic toxins p-cresyl sulfate and indoxyl sulfate due to their high degree of albumin binding. Ibuprofen, which shares the same primary albumin binding site with p-cresyl sulfate and indoxyl sulf...

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Опубликовано в: :Clin J Am Soc Nephrol
Главные авторы: Madero, Magdalena, Cano, Karla B., Campos, Israel, Tao, Xia, Maheshwari, Vaibhav, Brown, Jillian, Cornejo, Beatriz, Handelman, Garry, Thijssen, Stephan, Kotanko, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2019
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419294/
https://ncbi.nlm.nih.gov/pubmed/30755453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05240418
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