Complement Gene Variants and Shiga Toxin–Producing Escherichia coli–Associated Hemolytic Uremic Syndrome: Retrospective Genetic and Clinical Study

BACKGROUND AND OBJECTIVES: Inherited complement hyperactivation is critical for the pathogenesis of atypical hemolytic uremic syndrome (HUS) but undetermined in postdiarrheal HUS. Our aim was to investigate complement activation and variants of complement genes, and their association with disease se...

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Enregistré dans:
Détails bibliographiques
Publié dans:Clin J Am Soc Nephrol
Auteurs principaux: Frémeaux-Bacchi, Véronique, Sellier-Leclerc, Anne-Laure, Vieira-Martins, Paula, Limou, Sophie, Kwon, Theresa, Lahoche, Annie, Novo, Robert, Llanas, Brigitte, Nobili, François, Roussey, Gwenaëlle, Cailliez, Mathilde, Ulinski, Tim, Deschênes, Georges, Alberti, Corinne, Weill, François-Xavier, Mariani, Patricia, Loirat, Chantal
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419292/
https://ncbi.nlm.nih.gov/pubmed/30674459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05830518
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