Complement Gene Variants and Shiga Toxin–Producing Escherichia coli–Associated Hemolytic Uremic Syndrome: Retrospective Genetic and Clinical Study

BACKGROUND AND OBJECTIVES: Inherited complement hyperactivation is critical for the pathogenesis of atypical hemolytic uremic syndrome (HUS) but undetermined in postdiarrheal HUS. Our aim was to investigate complement activation and variants of complement genes, and their association with disease se...

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Veröffentlicht in:Clin J Am Soc Nephrol
Hauptverfasser: Frémeaux-Bacchi, Véronique, Sellier-Leclerc, Anne-Laure, Vieira-Martins, Paula, Limou, Sophie, Kwon, Theresa, Lahoche, Annie, Novo, Robert, Llanas, Brigitte, Nobili, François, Roussey, Gwenaëlle, Cailliez, Mathilde, Ulinski, Tim, Deschênes, Georges, Alberti, Corinne, Weill, François-Xavier, Mariani, Patricia, Loirat, Chantal
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419292/
https://ncbi.nlm.nih.gov/pubmed/30674459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05830518
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