Complement Gene Variants and Shiga Toxin–Producing Escherichia coli–Associated Hemolytic Uremic Syndrome: Retrospective Genetic and Clinical Study

BACKGROUND AND OBJECTIVES: Inherited complement hyperactivation is critical for the pathogenesis of atypical hemolytic uremic syndrome (HUS) but undetermined in postdiarrheal HUS. Our aim was to investigate complement activation and variants of complement genes, and their association with disease se...

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Detalhes bibliográficos
Publicado no:Clin J Am Soc Nephrol
Main Authors: Frémeaux-Bacchi, Véronique, Sellier-Leclerc, Anne-Laure, Vieira-Martins, Paula, Limou, Sophie, Kwon, Theresa, Lahoche, Annie, Novo, Robert, Llanas, Brigitte, Nobili, François, Roussey, Gwenaëlle, Cailliez, Mathilde, Ulinski, Tim, Deschênes, Georges, Alberti, Corinne, Weill, François-Xavier, Mariani, Patricia, Loirat, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419292/
https://ncbi.nlm.nih.gov/pubmed/30674459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.05830518
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