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Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy

KEY POINTS: NMDA receptors are neurotransmitter‐gated ion channels that are critically involved in brain cell communication. Variations in genes encoding NMDA receptor subunits have been found in a range of neurodevelopmental disorders. We investigated a de novo genetic variant found in patients wit...

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Библиографические подробности
Опубликовано в: :J Physiol
Главные авторы: Marwick, Katie F. M., Hansen, Kasper B., Skehel, Paul A., Hardingham, Giles E., Wyllie, David J. A.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418762/
https://ncbi.nlm.nih.gov/pubmed/30604514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277292
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