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The human NMDA receptor GluN2A(N615K) variant influences channel blocker potency
N‐methyl‐D‐aspartate (NMDA) receptors are glutamate receptors with key roles in synaptic plasticity, due in part to their Mg(2+) mediated voltage‐dependence. A large number of genetic variants affecting NMDA receptor subunits have been found in people with a range of neurodevelopmental disorders, in...
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| Publicado no: | Pharmacol Res Perspect |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6584472/ https://ncbi.nlm.nih.gov/pubmed/31249692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.495 |
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