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μ‐Opioid receptors in primary sensory neurons are essential for opioid analgesic effect on acute and inflammatory pain and opioid‐induced hyperalgesia
KEY POINTS: μ‐Opioid receptors (MORs) are expressed peripherally and centrally, but the loci of MORs responsible for clinically relevant opioid analgesia are uncertain. Crossing Oprm1 (flox/flox) and Advillin (Cre/+) mice completely ablates MORs in dorsal root ganglion neurons and reduces the MOR ex...
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| Publicado en: | J Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6418757/ https://ncbi.nlm.nih.gov/pubmed/30578671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277428 |
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