Mixed chimerism established by hematopoietic stem cell transplantation is maintained by host and donor T regulatory cells

Transplantation is an effective treatment of many clinical disorders, but the mechanisms that regulate immunological tolerance are uncertain and remain central to improving patient outcome. Hemopoietic stem cell transplantation (SCT) often establishes “mixed chimerism” in which immune cells from bot...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Kinsella, Francesca A. M., Zuo, Jianmin, Inman, Charlotte F., Pearce, Hayden, Maggs, Luke, Eldershaw, Suzy E., Chan, Y. L. Tracey, Nunnick, Jane, Nagra, Sandeep, Griffiths, Mike, Craddock, Charles, Malladi, Ram, Moss, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418492/
https://ncbi.nlm.nih.gov/pubmed/30824417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018025502
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